I don't think you need 2.

Bear says that there is Datura all over Southern California, anywhere rural or urban. It's very common. Jimsomweed is potent enough that just getting the sap on your habds can make you sick. Bear pulled one out of his front yard without knowing what it was, it had an American football shaped tuber 18 inches underground. He became woosie and things "didn't look right" for hours afterwards.

Alice glances over to Ashley
Hey where did you buy that book? Looks expensive!

I figured we wouldn't make it to the rest stop today. Looks like we gotta leave really early tomorrow. I wonder if that stable guy will let us keep the mules there for another night without having to pay. I still don't see why those divas' lodging costs more than twice each than our room for 4.

Alice spots Elizabeth
Good morning!
Yeah obviously I'll take that breakfast too!

So what else can we do today?
You wanna visit that bath again, Yulya?
I need to find more glass shards and old clothing for wicks, I don't see why we should pay for trash. If you want I can show you how to make poisonous arrows. I'm not good with identifying plants of that world, that's Cat's job. But I can tell you what substances are inside a plant and how to process them into something useful.

That's easy, we'll just make a random list of unrelated poisonous plants randomly off the internet.

Water Hemlock, Oleander, Deadly Nightshade (Belladonna), Poison Ivy, Ricin, Bitter Almond and Datura.

Done.

This kills the host

It depends on the weather.
In bad weather we manage 3x 2h per week but in nice weather I'd rather be outside so it's more 1-2x

You can stop along the side of the road in many spots. You will find periodic rest areas with remnants of camping such as piles of wood and rock rings, but most traders stick in a convoy and arrive at the rest area together for  sdded safety.

The bullseye lanterns are a good choice and needed with animals not used to pulling at night, if you want to train them, pull past dusk until they begin to become wary.

Mules and other equines may refuse to move and dig in, start kicking, panic and run, or start breying loudly, rear up, reverse, become inconsolable for a time. The aftermath of pushing a mule too hard may be lingering issues.

So the bullseye lamp gives them a bright, wide, forward view which is reassuring so they may not even care that it's dark.

I'm going to say Gundren's cart had them but you didn't need them.